L-Glutamine Produced by Thorne Research
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Do you suffer of food allergies? Do you often develop fatigue, frequent flu-like symptoms, a mild elevation in body temperature and aching joints after a meal? Does your mind feel dull and fuzzy after eating certain foods, making it difficult or impossible for you to concentrate? You are most likely suffering of Leaky Gut Syndrome.
The condition known as leaky gut syndrome (intestinal hyper-permeability and dietary leukocytosis ) is characterized by a breakdown of the integrity of the cells lining the interior of the small intestines allowing large food molecules to enter the systemic circulation and provoking immune responses when various foods are ingested. This syndrome is responsible for many seemingly unrelated illnesses such as so called food allergies, fatigue, flu-like symptoms, elevation of body temperature after eating, joint and soft tissue pain, stuffy sinuses and brain fog. Some individuals exhibit many or all of these symptoms, others exhibit one or several and those in the more advanced
stages, exhibit far more symptoms than those listed here. It is the job of the enterocytes (cells that line the interior of the small intestine) to allow only digested food molecules of a very small size to be absorbed into the systemic circulation and to reject larger and perhaps only partially digested particles so that they may pass out of the system as waste.
When after years of faulty nutrition, often compounded by the destructive impact of yeast overgrowth these cells ( enterocytes ) begin to perform inadequately, many undesirable large food molecules gain entrance into the blood stream, provoking an immune response that requires an elevation in white blood cells ( dietary leukocytosis ). This taxes the immune system which now has to busy itself with cleaning up the undesirable invaders every time one eats, rather than being free to perform its normal protective functions. To make matters worse, many of these food macro molecules once in the blood, can trigger allergic reactions or impregnate themselves into healthy tissues (often in the joints) setting up the pre-conditions for arthritis later in life or causing flare-ups in already existing rheumatoid arthritic or other auto-immune conditions.
L-Glutamine, an amino acid supplement, is the most ideal nutrient for the regeneration of the enterocytes.
Interestingly enough, these enterocytes are the only cells in the body that do not derive their nutrients from the blood plasma, but rather ingest nutrients directly from the predigested food passing through the intestines. Therefore, if one's diet is rich in L-Glutamine, the intestinal cells can absorb it directly, thereby helping themselves to return to normal functional capacity and a return of the gut lining's integrity. It may take several months of daily L-Glutamine supplementation to heal a hyper-permeable intestine, but with good diet and a few other co-factors some results will be noticeable within a few weeks. Many of our patients have also reported that regular use of L-Glutamine has helped them to control their cravings for sweets and starches.
For best results, yeast overgrowth must be addressed, wheat gluten must be avoided and comprehensive essential fatty acid supplementation should be undertaken, please see Flax / Borage Oil
TO ENHANCE THIS SUPPLEMENT'S HEALING POTENTIAL: Avoid all wheat products (this includes pasta and bagels) foods containing chemicals, white sugar, dairy unless you are blood type "B", coffee, colas and all non-steroidal anti-inflammatory drugs.
If you know your blood type, Read Peter D'Adamo's "Eat Right For Your Type" eat apples, preferably organically grown Granny Smith (high in pectin, low in sugar content, good for enterocytes) or a fruit pectin supplement, a comprehensive essential fatty acid supplement such as our Flax / Borage Oil and use a high grade multi vitamin / mineral supplement such as Basic Nutrients III.
UI - 96428090
AU - Fraga Fuentes MD ; de Juana Velasco P ; Pintor Recuenco R
TI - [Metabolic role of glutamine and its importance in nutritional
AB - The advances in the field of nutritional support have made
certain nutrients very relevant, which, although they have been
known for a long time, at present represent an important chapter
in nutrition, entering into what is known as "nutritional
pharmacology". Among these nutrients is glutamine, an amino acid
classified as non-essential, but which in certain circumstances
may become to be considered as an "essential nutrient". In the
present review, a review is made of its metabolic role, synthesis
and degradation, metabolic routes and functions under normal
conditions as well as under critical conditions. It is known that
glutamine stimulates the synthesis and inhibits the degradation
of proteins, it is an important vehicle for the transport of
nitrogen and carbon within the tissues, it stimulates the
synthesis of hepatic glycogen, it is an energy source for cell
division, for the growth of different cells of rapid replication,
such as enterocytes, colonocytes, and fibroblasts, as well as for
other cells of the immune system, such as lymphocytes and
macrophages. Thus its role in the maintenance of structure, in
metabolism and function of the intestinal mucosa, and in
dysfunctions of the immune system. In parenteral nutrition, at
present there are no preparations which include it, given the
stability problems which it presents, although attempts have been
made to resolve this, using different possibilities, such as
di-peptides. However, in enteral nutrition, the diets tend to
include it, although in a small proportion. Nevertheless, having
recognized its beneficial role in a certain type of patients, at
present there are diets which contain glutamine in higher doses,
with the object of attempting to cover the increased demands of
glutamine which shall arise in these situations. The inclusion of
glutamine in nutritional therapy is supported by multiple studies
which reflect the beneficial effect of this nutrient, both in
enteral nutrition as in parenteral nutrition.
RF - REVIEW ARTICLE: 99 REFS.
RN - 0 (Proteins) ; 6899-04-3 (Glutamine)
MH - Bacterial Translocation ; English Abstract ; Enteral Nutrition ;
Glutamine/METABOLISM/*PHYSIOLOGY/*THERAPEUTIC USE ; Human ;
Parenteral Nutrition ; Proteins/METABOLISM
SO - Nutr Hosp 1996 Jul-Aug;11(4):215-25
SUGGESTED USE: Capsules, 2-3 capsules, 2 to 3 times daily, best taken an hour before meals.
INGREDIENTS: Each Capsule contains 500 mg L-Glutamine
Powder, 1/2 to 2 teaspoons, taken 2-3 times daily, best taken an hour before meals.
DRUG INTERACTIONS: None known.
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We specialize in candida related conditions and digestive disorders: candida albicans, candidiasis, chronic fatigue, fibromyalgia, fungal infection, thrush, systemic yeast,|
vaginal yeast infection and other common types of yeast infection, acid reflux, GERD, H pylori, helicobacter pylori, intestinal yeast overgrowth, leaky gut syndrome and stomach ulcer.
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professional's advice. It is derived from our clinical experience and may shed light on your
health complaints. In case of serious ailments which may not respond favorably, please
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